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# For SE Asia
I'd go with Malarone. They are very effective and have nothing like the evil side-effects of doxycyclin etc, though they're not cheap. Definitely better than malaria though

*EDIT* also make sure you have plenty of mossie-repellent. I found one based on eucalyptus oil very effective and it doesn't melt clothes like deet
(, Thu 16 Apr 2009, 13:42, archived)
# thanks for that
right - off to the nurse to talk about jabs
(, Thu 16 Apr 2009, 13:45, archived)
# She may mention something about feeling a little prick
don't take it personally
(, Thu 16 Apr 2009, 13:47, archived)
# I second Malarone
Worked fine for me, also experienced no side effects. Recommended by my Doctor and my father (who is also a GP).
(, Thu 16 Apr 2009, 13:51, archived)
# DEET is fucking evil

The way my fingers felt every time I used it (even after washing them thoroughly) told me quite enough. It also ruined a couple of clothing items.
(, Thu 16 Apr 2009, 13:54, archived)
# ^ THIS
Utterly.
(, Thu 16 Apr 2009, 13:56, archived)
# Yup
very nasty. The eucalyptus stuff smells better too. Citronella is pish though
(, Thu 16 Apr 2009, 13:58, archived)
# yes!
it can melt through certain plastics... horrible stuff.
(, Thu 16 Apr 2009, 14:01, archived)
# Marmite (if you can eat the stuff) keeps the mossies away completely.
couple of bits of bread per day with marmite on, you're sorted.

Edit: Internally applied, of course ;-)
(, Thu 16 Apr 2009, 13:54, archived)
# is there anything the stuff can't do?

(, Thu 16 Apr 2009, 13:57, archived)
# I'm still researching..
;-)
(, Thu 16 Apr 2009, 13:58, archived)
# This seems good
"Recently, a new type of antimalarial drug has also been available which is very effective since no mosquito populations have already generated resistance due to exposure. The new drug is called Atovaquone. Also, the drug has no side-effects" ( = Malarone)
Vs.
"Mefloquine may have severe and permanent adverse side-effects. It is known to cause severe depression, anxiety, paranoia, aggression, nightmares, insomnia, seizures, birth defects, peripheral motor-sensory neuropathy,[2] vestibular (balance) damage and central nervous system problems." ( = Larium)
(, Thu 16 Apr 2009, 13:59, archived)
# peripheral motor-sensory neuropathy!!
I don't quite know what that is, but it sounds very bad.

like the effects of leprosy, or something.
(, Thu 16 Apr 2009, 14:03, archived)
# makes your hands and feet go numb
and painful and in bad cases can end up in amputation. My father has it in relation to his diabetes.
(, Thu 16 Apr 2009, 14:09, archived)
# Regrettably I can't read the cited article without a journal subscription
but I suspect it means people started falling over a lot, and couldn't speak properly or pick things up. Sounds like being drunk, in fact. Except peripheral would mean it doesn't affect the brain. So like being drunk without the euphoria.
(, Thu 16 Apr 2009, 14:13, archived)
# It's more like
having permanent, painful pins and needles my father says but in very bad cases, like in Hanson's disease it is very easy for sufferers to damage the extremities ( my father is not even allowed to cut his own nails ( not that he could reach his toes ) for fear of damaging them) and in cases where people don't look after themselves to well before you know it you have gangrene in your limbs.
(, Thu 16 Apr 2009, 14:16, archived)
# Irritating, the ability of meaningless illness-related pain to persist forever.
You might think that eventually you could learn to ignore it, like start thinking "this is just an erroneous nerve signal I've been getting for years now and I'm no longer going to let it bother me," but no.
(, Thu 16 Apr 2009, 14:30, archived)